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ISIS Deuteration Facility

ISIS Neutron and Muon Source

The ISIS Deuteration Facility is able to produce deuterated samples for neutron experiments. The laboratory itself is well equipped with synthetic and analytical equipment.
The laboratory staff have a broad range of chemical expertise in synthesising per(deuterated) long-chain molecules up to C20 (including odd-numbered chains), covering fatty acids, alcohols, bromoalkanes, alkyl trichlorosilanes and other related species. They also have considerable experience in the synthesis of (per)deuterated ionic and non-ionic surfactants; carbohydrate and phosphorus chemistry; lipid and short peptides.

Deuteration capabilities

  • Hydrothermal pressure reactors
  • Synthesis
  • Microwave
Key molecules

User access

User program

Two proposal calls per year (April and October)

Access modes
Proposal system

Open to the ISIS user community.



ISIS Neutron and Muon Source
Rutherford Appleton Laboratory
Harwell Campus, Didcot
OX11 0QX


Deuteration Facility Manager